The HyBrow (Hypothesis Browser) system is a prototype bioinformatics tool for designing hypotheses and evaluating them for consistency with existing knowledge. HyBrow consists of a modeling framework with the ability to accommodate diverse biological information sources an event-based ontology for representing biological processes at different levels of detail a database to query information in the ontology and programs to perform hypothesis design and evaluation.There are five key components involved in making HyBrow work.# The Event-based ontology for representing biological knowledge# The Discreet Event Systems based conceptual framework which provides the theory that allows us to make statements in a context free formal language (made up of the ontology) and evaluate the statements for validity using constraints declared on existing data# The rule library that provides the steps to apply those constraints and decide support contradiction or no comment.# The relational database that stores existing information structured into the ontology.# The user interface.
HyBrow (Hypothesis Browser)
Software or tool development phase:
Stanford University; California; USA